Search on: BASEMENT MEMBRANE 
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Descriptor English:   Basement Membrane 
Descriptor Spanish:   Membrana Basal 
Descriptor Portuguese:   Membrana Basal 
Synonyms English:   Basal Lamina
Basement Lamina  
Tree Number:   A10.272.220
A10.615.179
Definition English:   A darkly stained mat-like EXTRACELLULAR MATRIX (ECM) that separates cell layers, such as EPITHELIUM from ENDOTHELIUM or a layer of CONNECTIVE TISSUE. The ECM layer that supports an overlying EPITHELIUM or ENDOTHELIUM is called basal lamina. Basement membrane (BM) can be formed by the fusion of either two adjacent basal laminae or a basal lamina with an adjacent reticular lamina of connective tissue. BM, composed mainly of TYPE IV COLLAGEN; glycoprotein LAMININ; and PROTEOGLYCAN, provides barriers as well as channels between interacting cell layers. 
Indexing Annotation English:   do not confuse X ref BASAL LAMINA with "lamina basalis", the basal plate of the embryonic neural tube
History Note English:   67(65) 
Allowable Qualifiers English:  
AB abnormalities AH anatomy & histology
BS blood supply CH chemistry
CY cytology DE drug effects
EM embryology EN enzymology
GD growth & development IM immunology
IN injuries IR innervation
ME metabolism MI microbiology
PS parasitology PA pathology
PH physiology PP physiopathology
RE radiation effects RA radiography
RI radionuclide imaging SE secretion
SU surgery TR transplantation
US ultrasonography UL ultrastructure
VI virology  
Record Number:   1507 
Unique Identifier:   D001485 

Occurrence in VHL:
 

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